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Cheap flights from Panama City to Madrid, Spain from C$ 744

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAD
16 abr. — 23 abr.1
1 adult

Cheapflights Tip: The best prices from Panama City Tocumen Intl to Madrid Barajas are usually found in March or February, booked 58 days in advance, depart on a Wednesday or Thursday and return on a Monday

Cheap flight deals from Panama City to Madrid

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Madrid (MAD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 11 abril 2025.

Round-trip from

C$ 974

One-way from

C$ 744

Popular in

December

Cheapest in

March

Average price

C$ 1,014

Good round-trip deal

C$ 3,127 or less
KLM
  • KLM
  • 4/6-16/6
  • 2 total stops
  • 59h 10m total
  • Panama City to Madrid
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Air Europa
  • Air Europa
  • 4/7
  • Nonstop
  • 9h 50m total
  • Panama City to Madrid
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Highest demand for flights based on searches. 4% potential increase in price (C$ 69 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease (C$ 21 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Panama City Tocumen Intl to Madrid Barajas.
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Find flight deals from Panama City to Madrid

Cheapest flights from Panama City to Madrid
Explore the most affordable flight options available from Panama City to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 11 abril 2025.

mié. 4/66:50 p.m.PTY - MAD
1 stop31h 45mKLM
lun. 16/68:25 p.m.MAD - PTY
1 stop27h 25mKLM
Deal found 10/4C$ 974
dom. 1/67:55 p.m.PTY - MAD
1 stop13h 50mMultiple Airlines
jue. 12/610:20 a.m.MAD - PTY
1 stop37h 30mMultiple Airlines
Deal found 10/4C$ 976
dom. 25/58:25 p.m.PTY - MAD
Nonstop9h 50mAir Europa
lun. 9/63:05 p.m.MAD - PTY
Nonstop10h 35mAir Europa
Deal found 10/4C$ 1,015
jue. 10/77:55 p.m.PTY - MAD
1 stop13h 50mAir France
lun. 1/96:00 a.m.MAD - PTY
1 stop18h 45mAir France
Deal found 10/4C$ 1,054
lun. 19/58:00 p.m.PTY - MAD
1 stop37h 50mTurkish Airlines
lun. 2/66:20 p.m.MAD - PTY
2 stops31h 00mTurkish Airlines
Deal found 10/4C$ 1,155
lun. 23/69:45 a.m.PTY - MAD
1 stop16h 15mUnited Airlines
vie. 25/712:45 p.m.MAD - PTY
2 stops32h 05mUnited Airlines
Deal found 9/4C$ 1,186
mié. 16/43:20 a.m.PTY - MAD
1 stop13h 10mAvianca
vie. 2/59:40 a.m.MAD - PTY
1 stop13h 50mAvianca
Deal found 10/4C$ 1,362

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 11 abril 2025.
Use the filters below to find and compare flights from Panama City to Madrid that are best for you.

Fly from

Panama City

Fly to

Madrid

Route

Depart

Return

Price

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

mié. 4/6

6:50 p.m.-9:35 a.m.

1 stop31h 45m

Madrid Barajas

lun. 16/6

8:25 p.m.-4:50 p.m.

1 stop27h 25m

C$ 974

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

dom. 1/6

7:55 p.m.-4:45 p.m.

1 stop13h 50m

Madrid Barajas

mar. 10/6

10:20 a.m.-4:50 p.m.

1 stop37h 30m

C$ 976

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

dom. 25/5

8:25 p.m.-1:15 p.m.

Nonstop9h 50m

Madrid Barajas

lun. 9/6

3:05 p.m.-6:40 p.m.

Nonstop10h 35m

C$ 1,015

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

jue. 10/7

7:55 p.m.-4:45 p.m.

1 stop13h 50m

Madrid Barajas

lun. 1/9

6:00 a.m.-5:45 p.m.

1 stop18h 45m

C$ 1,054

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

lun. 19/5

8:00 p.m.-1:35 p.m.

1 stop34h 35m

Madrid Barajas

lun. 2/6

12:00 p.m.-6:20 p.m.

2 stops37h 20m

C$ 1,155

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

lun. 23/6

9:45 a.m.-9:00 a.m.

1 stop16h 15m

Madrid Barajas

vie. 25/7

12:45 p.m.-1:50 p.m.

2 stops32h 05m

C$ 1,186

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

vie. 30/5

3:25 a.m.-11:30 p.m.

1 stop13h 05m

Madrid Barajas

mié. 27/8

9:40 a.m.-4:30 p.m.

1 stop13h 50m

C$ 1,415

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

vie. 4/7

8:25 p.m.-1:15 p.m.

Nonstop9h 50m

C$ 744

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

vie. 25/4

9:55 p.m.-1:35 p.m.

1 stop32h 40m

C$ 776

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

lun. 5/5

1:30 p.m.-2:05 p.m.

2 stops17h 35m

C$ 856

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 11 results
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Best time to book a flight from Panama City to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Madrid

How far ahead should I book a flight from Panama City to Madrid?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Madrid. Price data was last updated on 4 April 2025.

The best time to book flights from Panama City to Madrid is 58 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Panama City to Madrid?

Currently, November is the cheapest month in which you can book a flight from Panama City to Madrid (average of C$ 658). Flying from Panama City to Madrid in December is currently the most expensive (average of C$ 951). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to MAD?

Find hourly flight availability from Panama City to Madrid. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 11 abril 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 5% on flights from Panama City to Madrid by exploring options for tickets in the morning.

Weekly flight availability from Panama City to Madrid

Explore weekly flight availability from Panama City to Madrid. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 11 abril 2025.

The most flights from PTY to MAD are scheduled on a Monday (8 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (3 on average).

Rainfall in Madrid by month

Plan your trip to Madrid by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Madrid ranges from 10.0 - 60.0 mm per month. November is typically the wettest month, when rainfall can reach 60.0 mm. July is typically the driest time to visit Madrid when rainfall is around 10.0 mm.

Temperature in Madrid by month

Plan your trip to Madrid by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Madrid, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 25.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 5.0 C).

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated 11 abril 2025.
To help decide which airline to fly from Panama City to Madrid, see what other customers have to say about KLM, Air France and United Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,321 reviews
Check prices

Food

7.3

Entertainment

7.1

Boarding

7.8

Crew

8.4

Overall

7.8

Comfort

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
KLM
7.8
Good
1,321 reviews
KLM
7.8
Good
1,321 reviews
Check prices

Food

7.3

Entertainment

7.1

Boarding

7.8

Crew

8.4

Overall

7.8

Comfort

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
Air France
7.4
Good
1,428 reviews
KLM
7.8
Good
1,321 reviews
Check prices

Food

7.3

Entertainment

7.1

Boarding

7.8

Crew

8.4

Overall

7.8

Comfort

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
United Airlines
7.4
Good
8,636 reviews
KLM
7.8
Good
1,321 reviews
Check prices

Food

7.3

Entertainment

7.1

Boarding

7.8

Crew

8.4

Overall

7.8

Comfort

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
Turkish Airlines
7.3
Good
3,753 reviews
KLM
7.8
Good
1,321 reviews
Check prices

Food

7.3

Entertainment

7.1

Boarding

7.8

Crew

8.4

Overall

7.8

Comfort

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
Iberia
7.0
Good
2,669 reviews
KLM
7.8
Good
1,321 reviews
Check prices

Food

7.3

Entertainment

7.1

Boarding

7.8

Crew

8.4

Overall

7.8

Comfort

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Panama City to Madrid?

    To fly from Panama City to Madrid, you need to book a flight from Tocumen Intl (PTY) to Barajas (MAD). Nonstop flights to Madrid Barajas from Panama City Tocumen Intl take 9h 50m on average. When it comes time to book airfare, you have a few options: there are 4 outbound flights from Tocumen Intl to Barajas offered by 2 different airlines.

  • How popular is this Panama City to Madrid flight route?

    This flight path from Panama City Tocumen Intl to Madrid Barajas was viewed by 6 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Panama City to Madrid round-trip?

    Cheapflights users have booked flights from Panama City to Madrid round-trip from C$ 974. Other airlines that can offer you cheap pricing are Air Europa, from C$ 1,015, and Air France, from C$ 1,054. KLM is currently priced 9% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Panama City to Madrid one-way?

    For one-way options, check prices for Air Europa. According to our data, you can fly for as low as C$ 744. Users have also found prices from C$ 776 and C$ 856 on Turkish Airlines and Avianca, respectively.

  • What are the most reliable airlines from Panama City to Madrid?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Panama City to Madrid on time: Qatar Airways (83%), Iberia (83%), EL AL (83%).

  • What are the cheapest flights from Panama City to Madrid?

    On average you can expect to pay C$ 3,365 for a flight from Panama City to Madrid. The cheapest flight overall is C$ 3,125 while the most popular route, (Panama City Tocumen Intl - Madrid Barajas) is currently priced at C$ 1,071.

  • Can I find deals for flights from Panama City to Madrid that include hotel bookings?

    Yes. In addition to deals on Panama City to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Madrid.

  • Can I find deals for business class flights from Panama City to Madrid?

    Yes. Cheapflights offers flight deals from Panama City to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Madrid?

    Currently, November is the cheapest month in which you can book a flight from Panama City to Madrid (average of C$ 658). Flying from Panama City to Madrid in December is currently the most expensive (average of C$ 951). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Panama City to Madrid

Discover the top 2 airlines that operate flights from Panama City to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 11 abril 2025.
AirlineCheapestAverageFlexibilityOn-time
IberiaCheapestC$ 992AverageC$ 1,101FlexibilityNo cancel feeOn-time77%
Search Iberia flights
Air EuropaCheapestC$ 1,063AverageC$ 2,648FlexibilityNo cancel feeOn-time83%
Search Air Europa flights

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Can Cheapflights find flights from Panama City to Madrid with no change fees?

Need flexible booking options for your flight to Madrid from Panama City? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Panama City to Madrid become cheaper?

Yes, Cheapflights offers price alerts on Panama City to Madrid flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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