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Cheap flights from Mexico City to Panama City from C$ 314

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 22/3. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — PTY
26 Feb — 5 Mar1
1 adult

The best prices from Mexico City Benito Juarez to Panama City Tocumen Intl are usually found in February or March, booked 54 days in advance, depart on a Saturday or Wednesday and return on a Monday

Cheap flight deals from Mexico City to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 21 February 2025.

Round-trip from

C$ 641

One-way from

C$ 314

Popular in

July

Cheapest in

February

Average price

C$ 615

Good round-trip deal

C$ 506 or less

Good one-way deal

C$ 302 or less
Avianca
  • Avianca
  • 3/3-7/3
  • 2 total stops
  • 24h 20m total
  • Mexico City to Panama City
Avianca
  • Avianca
  • 22/3
  • 1 total stop
  • 14h 50m total
  • Mexico City to Panama City
Highest demand for flights based on searches. 9% potential increase in price (C$ 104 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease (C$ 14 potential savings vs. average RT price).
Average for round-trip flights in February 2025
Price to beat on a round-trip flight from Mexico City Benito Juarez to Panama City Tocumen Intl.
Price to beat on a one-way flight from Mexico City Benito Juarez to Panama City Tocumen Intl.

Find flight deals from Mexico City to Panama City

Cheapest flights from Mexico City to Panama City
Explore the most affordable flight options available from Mexico City to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 February 2025.

Mon 3/312:40 a.m.MEX - PTY
1 stop14h 50mAvianca
Fri 7/36:30 p.m.PTY - MEX
1 stop9h 30mAvianca
Deal found 21/2C$ 641
Fri 11/42:00 a.m.MEX - PTY
Nonstop3h 46mCopa Airlines
Sun 27/49:23 p.m.PTY - MEX
Nonstop3h 52mCopa Airlines
Deal found 20/2C$ 689
Thu 14/88:55 a.m.MEX - PTY
Nonstop3h 52mAeromexico
Wed 20/83:02 p.m.PTY - MEX
Nonstop3h 38mAeromexico
Deal found 20/2C$ 724
Tue 4/311:15 p.m.MEX - PTY
3 stops34h 10mMultiple Airlines
Fri 7/38:05 p.m.PTY - MEX
2 stops22h 50mMultiple Airlines
Deal found 21/2C$ 852
Sun 6/44:40 a.m.MEX - PTY
1 stop10h 32mUnited Airlines
Sun 13/410:00 a.m.PTY - MEX
1 stop14h 10mUnited Airlines
Deal found 20/2C$ 1,601

Find flights from Mexico City to Panama City within your budget

Customize your flight search to find flights from Mexico City to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 21 February 2025.

Fly from

Mexico City

Fly to

Panama City

Route

Depart

Return

Price

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Mon 3/3

12:40 a.m.-4:30 p.m.

1 stop14h 50m

Panama City Tocumen Intl

Fri 7/3

6:30 p.m.-3:00 a.m.

1 stop9h 30m

C$ 641

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Fri 11/4

2:00 a.m.-6:46 a.m.

Nonstop3h 46m

Panama City Tocumen Intl

Sun 27/4

9:23 p.m.-12:15 a.m.

Nonstop3h 52m

C$ 689

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Thu 14/8

8:55 a.m.-1:47 p.m.

Nonstop3h 52m

Panama City Tocumen Intl

Wed 20/8

3:02 p.m.-5:40 p.m.

Nonstop3h 38m

C$ 724

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Tue 4/3

11:15 p.m.-10:25 a.m.

3 stops34h 10m

Panama City Tocumen Intl

Fri 7/3

8:05 p.m.-5:55 p.m.

2 stops22h 50m

C$ 852

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Sun 6/4

4:40 a.m.-4:12 p.m.

1 stop10h 32m

Panama City Tocumen Intl

Sun 13/4

10:00 a.m.-11:10 p.m.

1 stop14h 10m

C$ 1,601

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Sat 22/3

12:40 a.m.-4:30 p.m.

1 stop14h 50m

C$ 314

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Wed 12/3

1:20 a.m.-6:00 a.m.

Nonstop3h 40m

C$ 767

Flights are sorted by cheapest round-trip flights first.

Deals found on 20/2

Best time to book a flight from Mexico City to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Mexico City to Panama City

Get recent, data-driven insights about flights from Mexico City to Panama City including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Mexico City to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Mexico City to Panama City. Price data was last updated on 14 February 2025.

To ensure you get the cheapest price possible for a flight from Mexico City to Panama City, you should look to book at least 54 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Mexico City to Panama City?

Currently, January is the cheapest month in which you can book a flight from Mexico City to Panama City (average of C$ 542). Flying from Mexico City to Panama City in December is currently the most expensive (average of C$ 874). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MEX to PTY?

Find hourly flight availability from Mexico City to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 21 February 2025.

It’s typically best to fly out from Mexico City to Panama City in the morning. Doing so could potentially save you 39% on the flight price compared to flying in the afternoon, which is usually more expensive.

Weekly flight availability from Mexico City to Panama City

Explore weekly flight availability from Mexico City to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 21 February 2025.

The most flights from MEX to PTY are scheduled on a Wednesday (9 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 10.0 - 340.0 mm per month. October is typically the wettest month, when rainfall can reach 340.0 mm. February is typically the driest time to visit Panama City when rainfall is around 10.0 mm.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 26.0 C).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 21 February 2025.
To help decide which airline to fly from Mexico City to Panama City, see what other customers have to say about Copa Airlines, Aeromexico and United Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

6.9

Crew

8.1

Entertainment

6.9

Boarding

7.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Food

6.9

Crew

8.1

Entertainment

6.9

Boarding

7.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Food

6.9

Crew

8.1

Entertainment

6.9

Boarding

7.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Food

6.9

Crew

8.1

Entertainment

6.9

Boarding

7.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Food

6.9

Crew

8.1

Entertainment

6.9

Boarding

7.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airports do I use to fly from Mexico City to Panama City?

    Booking a flight from Mexico City Benito Juarez (MEX) to Panama City Tocumen Intl (PTY) is your only option if you wish to fly from Mexico City to Panama City. On a typical day, there are 6 flights from Benito Juarez to Tocumen Intl, all of which are around 3h 38m for a nonstop flight. You can also purchase a plane ticket from 1 airline when you book a flight from Benito Juarez to Panama City.

  • How popular is this Mexico City to Panama City flight route?

  • What are the cheapest airlines flying from Mexico City to Panama City round-trip?

    Flying on Avianca is currently your cheapest option to Panama City, with prices starting at C$ 641. Additional round-trip tickets that might be worth considering are offered by Copa Airlines and Aeromexico, with the lowest prices starting at C$ 689 and C$ 724, respectively. Users have found that Avianca is 5% cheaper than the other options available to this destination.

  • What are the cheapest flights from Mexico City to Panama City?

    The cheapest flight price from Mexico City to Panama City is C$ 258. On average you can expect to pay C$ 451. The most popular route, (Mexico City Benito Juarez - Panama City Tocumen Intl), can usually be booked for C$ 541.

  • Can I find deals for flights from Mexico City to Panama City that include hotel bookings?

    Yes. In addition to deals on Mexico City to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Panama City.

  • Can I find deals for business class flights from Mexico City to Panama City?

    Yes. Cheapflights offers flight deals from Mexico City to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Panama City?

    Currently, January is the cheapest month in which you can book a flight from Mexico City to Panama City (average of C$ 542). Flying from Mexico City to Panama City in December is currently the most expensive (average of C$ 874). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Mexico City to Panama City

Discover the top airline that operate flights from Mexico City to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 21 February 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapestC$ 569AverageC$ 636FlexibilityNo cancel feeOn-time70%
Search Copa Airlines flights

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