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Cheap flights from Mexico City to Panama City from C$ 317

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — PTY
30 Mar — 6 Apr1
1 adult

Cheapflights Tip: The best prices from Mexico City Benito Juarez to Panama City Tocumen Intl are usually found in February or January, booked 61 days in advance, depart on a Saturday or Wednesday and return on a Monday

Cheap flight deals from Mexico City to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 25 March 2025.

Round-trip from

C$ 582

One-way from

C$ 317

Popular in

July

Cheapest in

February

Average price

C$ 653

Good round-trip deal

C$ 583 or less

Good one-way deal

C$ 383 or less
Avianca
  • Avianca
  • 9/5-17/5
  • 3 total stops
  • 19h 30m total
  • Mexico City to Panama City
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Avianca
  • Avianca
  • 11/7
  • 1 total stop
  • 7h 15m total
  • Mexico City to Panama City
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Highest demand for flights based on searches. 8% potential increase in price (C$ 94 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease (C$ 14 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Price to beat on a round-trip flight from Mexico City Benito Juarez to Panama City Tocumen Intl.
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Price to beat on a one-way flight from Mexico City Benito Juarez to Panama City Tocumen Intl.
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Find flight deals from Mexico City to Panama City

Cheapest flights from Mexico City to Panama City
Explore the most affordable flight options available from Mexico City to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 25 March 2025.

Mon 31/312:40 a.m.MEX - PTY
1 stop7h 15mAvianca
Fri 4/45:25 p.m.PTY - MEX
1 stop10h 40mAvianca
Deal found 24/3C$ 562
Tue 22/41:40 a.m.MEX - PTY
Nonstop3h 38mCopa Airlines
Wed 30/411:43 a.m.PTY - MEX
Nonstop3h 47mCopa Airlines
Deal found 23/3C$ 583
Tue 1/412:55 p.m.MEX - PTY
1 stop6h 20mMultiple Airlines
Fri 4/47:08 p.m.PTY - MEX
Nonstop3h 52mMultiple Airlines
Deal found 24/3C$ 1,344

Cheapflights Fare Finder

Customize your flight search to find flights from Mexico City to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 25 March 2025.
Use the filters below to find and compare flights from Mexico City to Panama City that are best for you.

Fly from

Mexico City

Fly to

Panama City

Route

Depart

Return

Price

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Fri 9/5

12:55 p.m.-12:10 a.m.

2 stops10h 15m

Panama City Tocumen Intl

Fri 16/5

3:25 a.m.-12:05 p.m.

1 stop9h 40m

C$ 582

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Tue 22/4

1:40 a.m.-6:18 a.m.

Nonstop3h 38m

Panama City Tocumen Intl

Wed 30/4

11:43 a.m.-2:30 p.m.

Nonstop3h 47m

C$ 583

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Fri 11/7

12:40 a.m.-8:55 a.m.

1 stop7h 15m

C$ 317

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Sun 30/3

9:50 a.m.-2:36 p.m.

Nonstop3h 46m

C$ 774

Flights are sorted by cheapest round-trip flights first.

Deals found on 24/3

Best time to book a flight from Mexico City to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Panama City

How far ahead should I book a flight from Mexico City to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Mexico City to Panama City. Price data was last updated on 21 March 2025.

To ensure you get the cheapest price possible for a flight from Mexico City to Panama City, you should look to book at least 61 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Mexico City to Panama City?

Currently, January is the cheapest month in which you can book a flight from Mexico City to Panama City (average of C$ 542). Flying from Mexico City to Panama City in December is currently the most expensive (average of C$ 874). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MEX to PTY?

Find hourly flight availability from Mexico City to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 25 March 2025.

It’s typically best to fly out from Mexico City to Panama City in the morning. Doing so could potentially save you 44% on the flight price compared to flying in the afternoon, which is usually more expensive.

Weekly flight availability from Mexico City to Panama City

Explore weekly flight availability from Mexico City to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 25 March 2025.

The most flights from MEX to PTY are scheduled on a Tuesday (8 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 10.0 - 340.0 mm per month. October is typically the wettest month, when rainfall can reach 340.0 mm. February is typically the driest time to visit Panama City when rainfall is around 10.0 mm.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 26.0 C).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 25 March 2025.
To help decide which airline to fly from Mexico City to Panama City, see what other customers have to say about Copa Airlines and Avianca. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,393 reviews
Check prices

Crew

8.1

Overall

7.6

Boarding

7.8

Food

6.8

Comfort

7.4

Entertainment

6.8

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LIM - PTY

you go security buy an expensive bottle of water to take on the plane and then you have to go to another security point where they confiscate your water, the planes left on time and arrived on time. excellent food was mostly tasteless and overheated, no entertainment. wifi was glitchy.
Copa Airlines
7.6
Good
1,393 reviews
Copa Airlines
7.6
Good
1,393 reviews
Check prices

Crew

8.1

Overall

7.6

Boarding

7.8

Food

6.8

Comfort

7.4

Entertainment

6.8

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LIM - PTY

you go security buy an expensive bottle of water to take on the plane and then you have to go to another security point where they confiscate your water, the planes left on time and arrived on time. excellent food was mostly tasteless and overheated, no entertainment. wifi was glitchy.
Avianca
6.7
Okay
2,294 reviews
Copa Airlines
7.6
Good
1,393 reviews
Check prices

Crew

8.1

Overall

7.6

Boarding

7.8

Food

6.8

Comfort

7.4

Entertainment

6.8

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LIM - PTY

you go security buy an expensive bottle of water to take on the plane and then you have to go to another security point where they confiscate your water, the planes left on time and arrived on time. excellent food was mostly tasteless and overheated, no entertainment. wifi was glitchy.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Mexico City to Panama City?

    Booking a flight from Mexico City Benito Juarez (MEX) to Panama City Tocumen Intl (PTY) is your only option if you wish to fly from Mexico City to Panama City. On a typical day, there are 6 flights from Benito Juarez to Tocumen Intl, all of which are around 3h 38m for a nonstop flight. You can also purchase a plane ticket from 1 airline when you book a flight from Benito Juarez to Panama City.

  • How popular is this Mexico City to Panama City flight route?

    Flights from Mexico City Benito Juarez to Panama City Tocumen Intl have been viewed 12 times in the past calendar month.

  • What are the cheapest airlines flying from Mexico City to Panama City round-trip?

    Flying on Avianca is currently your cheapest option to Panama City, with prices starting at C$ 582. Another option worth looking into is Copa Airlines, starting at C$ 583 round trip. Users have found that Avianca is 15% cheaper than the other options available to this destination.

  • What are the cheapest flights from Mexico City to Panama City?

    The cheapest flight price from Mexico City to Panama City is C$ 307. On average you can expect to pay C$ 668. The most popular route, (Mexico City Benito Juarez - Panama City Tocumen Intl), can usually be booked for C$ 947.

  • Can I find deals for flights from Mexico City to Panama City that include hotel bookings?

    Yes. In addition to deals on Mexico City to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Panama City.

  • Can I find deals for business class flights from Mexico City to Panama City?

    Yes. Cheapflights offers flight deals from Mexico City to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Panama City?

    Currently, January is the cheapest month in which you can book a flight from Mexico City to Panama City (average of C$ 542). Flying from Mexico City to Panama City in December is currently the most expensive (average of C$ 874). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Mexico City to Panama City

Discover the top airline that operate flights from Mexico City to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 25 March 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapestC$ 583AverageC$ 642FlexibilityNo cancel feeOn-time70%
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Fly with Cheapflights

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How does Cheapflights help users find flights from Mexico City to Panama City?

Cheapflights makes it easy to find Mexico City to Panama City flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

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It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Mexico City to Panama City.

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