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Cheap flights from Santo Domingo to Panama City from C$ 294

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/4. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — PTY
30 Mar — 6 Apr1
1 adult

Cheap flight deals from Santo Domingo to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 25 March 2025.

Round-trip from

C$ 595

One-way from

C$ 294

Popular in

March

Cheapest in

May

Average price

C$ 713

Good round-trip deal

C$ 427 or less

Good one-way deal

C$ 289 or less
Copa Airlines
  • Copa Airlines
  • 15/4-22/4
  • Nonstop
  • 5h 05m total
  • Santo Domingo to Panama City
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Avianca
  • Avianca
  • 1/4
  • 1 total stop
  • 7h 00m total
  • Santo Domingo to Panama City
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Highest demand for flights based on searches. 9% potential increase in price (C$ 95 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease (C$ 11 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Price to beat on a round-trip flight from Santo Domingo Las Americas to Panama City Tocumen Intl.
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Price to beat on a one-way flight from Santo Domingo Las Americas to Panama City Tocumen Intl.
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Find flight deals from Santo Domingo to Panama City

Cheapest flights from Santo Domingo to Panama City
Explore the most affordable flight options available from Santo Domingo to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 25 March 2025.

Tue 1/45:14 a.m.SDQ - PTY
Nonstop2h 44mCopa Airlines
Mon 12/511:13 p.m.PTY - SDQ
Nonstop2h 32mCopa Airlines
Deal found 24/3C$ 595
Mon 26/511:45 a.m.SDQ - PTY
1 stop5h 45mAvianca
Thu 29/53:20 a.m.PTY - SDQ
1 stop12h 55mAvianca
Deal found 23/3C$ 645
Thu 25/91:10 p.m.SDQ - PTY
2 stops26h 09mUnited Airlines
Tue 30/910:00 a.m.PTY - SDQ
2 stops14h 50mUnited Airlines
Deal found 23/3C$ 2,031
Wed 10/92:09 p.m.SDQ - PTY
2 stops23h 40mDelta
Thu 18/92:14 p.m.PTY - SDQ
2 stops26h 37mDelta
Deal found 24/3C$ 9,309

Cheapflights Fare Finder

Customize your flight search to find flights from Santo Domingo to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 25 March 2025.
Use the filters below to find and compare flights from Santo Domingo to Panama City that are best for you.

Fly from

Santo Domingo

Fly to

Panama City

Route

Depart

Return

Price

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Tue 15/4

5:20 a.m.-6:58 a.m.

Nonstop2h 38m

Panama City Tocumen Intl

Tue 22/4

11:13 p.m.-2:40 a.m.

Nonstop2h 27m

C$ 595

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Mon 26/5

11:45 a.m.-4:30 p.m.

1 stop5h 45m

Panama City Tocumen Intl

Thu 29/5

3:20 a.m.-5:15 p.m.

1 stop12h 55m

C$ 645

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Tue 15/4

1:10 p.m.-2:14 p.m.

2 stops26h 04m

Panama City Tocumen Intl

Tue 29/4

7:55 a.m.-1:50 a.m.

2 stops16h 55m

C$ 2,188

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Wed 10/9

2:09 p.m.-12:49 p.m.

2 stops23h 40m

Panama City Tocumen Intl

Thu 18/9

2:14 p.m.-5:51 p.m.

2 stops26h 37m

C$ 9,309

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Tue 1/4

6:10 p.m.-12:10 a.m.

1 stop7h 00m

C$ 294

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Tue 1/4

11:51 a.m.-1:29 p.m.

Nonstop2h 38m

C$ 768

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Tue 1/4

1:10 p.m.-2:14 p.m.

2 stops26h 04m

C$ 2,440

Flights are sorted by cheapest round-trip flights first.

Deals found on 24/3

Best time to book a flight from Santo Domingo to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Panama City

How far ahead should I book a flight from Santo Domingo to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Panama City. Price data was last updated on 21 March 2025.

The best time to book flights from Santo Domingo to Panama City is 20 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santo Domingo to Panama City?

Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Panama City (average of C$ 542). Flying from Santo Domingo to Panama City in December is currently the most expensive (average of C$ 874). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to PTY?

Find hourly flight availability from Santo Domingo to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 25 March 2025.

It’s typically best to fly out from Santo Domingo to Panama City in the morning. Doing so could potentially save you 75% on the flight price compared to flying at noon, which is usually more expensive.

Weekly flight availability from Santo Domingo to Panama City

Explore weekly flight availability from Santo Domingo to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 25 March 2025.

The most flights from SDQ to PTY are scheduled on a Monday (9 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (5 on average).

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 10.0 - 340.0 mm per month. October is typically the wettest month, when rainfall can reach 340.0 mm. February is typically the driest time to visit Panama City when rainfall is around 10.0 mm.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 26.0 C).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 25 March 2025.
Delta
8.0
Very good
7,890 reviews
Check prices

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

ATL - JNB

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.
Delta
8.0
Very good
7,890 reviews
Delta
8.0
Very good
7,890 reviews
Check prices

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

ATL - JNB

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.
Copa Airlines
7.6
Good
1,393 reviews
Delta
8.0
Very good
7,890 reviews
Check prices

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

ATL - JNB

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.
United Airlines
7.4
Good
8,605 reviews
Delta
8.0
Very good
7,890 reviews
Check prices

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

ATL - JNB

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.
Avianca
6.7
Okay
2,294 reviews
Delta
8.0
Very good
7,890 reviews
Check prices

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

ATL - JNB

Bad experience with the staff boarding the gate. I couldn’t board with my carry on, personal item and a funny bag. I had to put my passport inside my pockets and put the funny bag inside the personal item. Then after passing the staff pull out everything again.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Santo Domingo to Panama City flight route?

    Flights from Santo Domingo Las Americas to Panama City Tocumen Intl have been viewed 33 times in the past calendar month.

  • What are the cheapest airlines flying from Santo Domingo to Panama City round-trip?

    Cheapflights users have booked flights from Santo Domingo to Panama City round-trip from C$ 595. Other airlines that can offer you cheap pricing are Avianca, from C$ 645, and United Airlines, from C$ 2,188. Copa Airlines is 5% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Santo Domingo to Panama City one-way?

    C$ 294 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on Copa Airlines and United Airlines, with prices starting from C$ 768 and C$ 2,440, respectively.

  • What are the most reliable airlines from Santo Domingo to Panama City?

    No one likes to see their flight delayed. When booking a flight from Santo Domingo to Panama City consider choosing Air France (100%), Copa Airlines (97%) or Turkish Airlines (97%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Santo Domingo to Panama City?

    The cheapest flight price from Santo Domingo to Panama City is C$ 258. On average you can expect to pay C$ 335. The most popular route, (Santo Domingo Las Americas - Panama City Tocumen Intl), can usually be booked for C$ 713.

  • Can I find deals for flights from Santo Domingo to Panama City that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Panama City.

  • Can I find deals for business class flights from Santo Domingo to Panama City?

    Yes. Cheapflights offers flight deals from Santo Domingo to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Panama City?

    Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Panama City (average of C$ 542). Flying from Santo Domingo to Panama City in December is currently the most expensive (average of C$ 874). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Can Cheapflights find flights from Santo Domingo to Panama City with no change fees?

Certainly. Search results for flights to Panama City from Santo Domingo shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Santo Domingo to Panama City become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Panama City from Santo Domingo today and book when prices fit your budget.

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