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Cheap flights from Mexico City to Santiago from C$ 749

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/3. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — SCL
22 Jan — 29 Jan1
1 adult

Cheap flight deals from Mexico City to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 17 January 2025.

Round-trip from

C$ 749

Popular in

December

Cheapest in

March

Average price

C$ 982
Copa Airlines
  • Copa Airlines
  • 19/3-26/3
  • 2 total stops
  • 38h 27m total
  • Mexico City to Santiago
High demand for flights, 7% potential price rise
Best time to find cheap flights, 1% potential price drop
Average for round-trip flights in January 2025

Find flight deals from Mexico City to Santiago

Cheapest flights from Mexico City to Santiago
Explore the most affordable flight options available from Mexico City to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 January 2025.

Wed 19/32:00 a.m.MEX - SCL
1 stop18h 55mCopa Airlines
Wed 26/35:33 a.m.SCL - MEX
1 stop19h 32mCopa Airlines
Deal found 15/1C$ 749
Fri 14/311:15 p.m.MEX - SCL
1 stop12h 05mAvianca
Thu 27/33:25 p.m.SCL - MEX
1 stop14h 35mAvianca
Deal found 16/1C$ 808
Fri 18/48:20 p.m.MEX - SCL
Nonstop8h 05mLATAM Airlines
Mon 21/48:10 a.m.SCL - MEX
Nonstop8h 45mLATAM Airlines
Deal found 16/1C$ 838
Sun 2/1110:05 a.m.MEX - SCL
Nonstop8h 10mAeromexico
Tue 18/1111:25 p.m.SCL - MEX
Nonstop8h 35mAeromexico
Deal found 15/1C$ 868
Fri 18/42:00 p.m.MEX - SCL
1 stop12h 15mMultiple Airlines
Sun 20/412:35 a.m.SCL - MEX
1 stop36h 45mMultiple Airlines
Deal found 16/1C$ 1,176
Wed 5/39:05 a.m.MEX - SCL
2 stops44h 45mUnited Airlines
Sun 9/39:45 p.m.SCL - MEX
2 stops50h 05mUnited Airlines
Deal found 16/1C$ 2,591

Find flights from Mexico City to Santiago within your budget

Customize your flight search to find flights from Mexico City to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 17 January 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Wed 19/3

2:00 a.m.-11:55 p.m.

1 stop18h 55m

Santiago Arturo Merino Benitez

Wed 26/3

5:33 a.m.-10:05 p.m.

1 stop19h 32m

C$ 749

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Fri 14/3

11:15 p.m.-2:20 p.m.

1 stop12h 05m

Santiago Arturo Merino Benitez

Thu 27/3

3:25 p.m.-3:00 a.m.

1 stop14h 35m

C$ 808

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Fri 18/4

8:20 p.m.-6:25 a.m.

Nonstop8h 05m

Santiago Arturo Merino Benitez

Mon 21/4

8:10 a.m.-2:55 p.m.

Nonstop8h 45m

C$ 838

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Fri 18/4

2:00 p.m.-4:15 a.m.

1 stop12h 15m

Santiago Arturo Merino Benitez

Sun 20/4

12:35 a.m.-11:20 a.m.

1 stop36h 45m

C$ 1,176

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Wed 5/3

10:10 a.m.-9:15 p.m.

Nonstop8h 05m

Santiago Arturo Merino Benitez

Sun 9/3

11:15 p.m.-4:45 a.m.

Nonstop8h 30m

C$ 1,186

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Wed 5/3

9:05 a.m.-8:50 a.m.

2 stops44h 45m

Santiago Arturo Merino Benitez

Sun 9/3

9:45 p.m.-8:50 p.m.

2 stops50h 05m

C$ 2,591

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Wed 30/4

3:20 p.m.-10:05 a.m.

2 stops40h 45m

Santiago Arturo Merino Benitez

Fri 20/6

12:40 a.m.-2:20 p.m.

3 stops63h 40m

C$ 42,624

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Mon 24/2

2:00 a.m.-8:19 p.m.

1 stop15h 19m

C$ 812

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Mon 24/2

10:05 a.m.-9:10 p.m.

Nonstop8h 05m

C$ 857

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Tue 25/2

6:40 a.m.-10:50 p.m.

3 stops37h 10m

C$ 933

Flights are sorted by cheapest round-trip flights first.

Deals found on 16/1

Showing 1-10 of 11 results
1
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Best time to book a flight from Mexico City to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Mexico City to Santiago

Get recent, data-driven insights about flights from Mexico City to Santiago including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Mexico City to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Mexico City to Santiago. Price data was last updated on 10 January 2025.

The price you pay for your flight from Mexico City to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 83 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Mexico City to Santiago?

Currently, April is the cheapest month in which you can book a flight from Mexico City to Santiago (average of C$ 628). Flying from Mexico City to Santiago in December is currently the most expensive (average of C$ 907). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MEX to SCL?

Find hourly flight availability from Mexico City to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 17 January 2025.

When flying from Mexico City to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Mexico City to Santiago

Explore weekly flight availability from Mexico City to Santiago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 17 January 2025.

The most flights from MEX to SCL are scheduled on a Monday (3 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 70.0 mm per month. June is typically the wettest month, when rainfall can reach 70.0 mm. January is typically the driest time to visit Santiago when rainfall is around 0.0 mm.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 21.0 C. Travellers hoping to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 8.0 C).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 17 January 2025.
To help decide which airline to fly from Mexico City to Santiago, see what other customers have to say about Copa Airlines and Aeromexico. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
7.7
Good
1,658 reviews

Comfort

7.5

Entertainment

6.9

Overall

7.7

Food

7.0

Crew

8.2

Boarding

7.9

Reviews

1 / 10

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

7.7
Good
1,658 reviews
7.7
Good
1,658 reviews

Comfort

7.5

Entertainment

6.9

Overall

7.7

Food

7.0

Crew

8.2

Boarding

7.9

Reviews

1 / 10

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

7.5
Good
1,849 reviews
7.7
Good
1,658 reviews

Comfort

7.5

Entertainment

6.9

Overall

7.7

Food

7.0

Crew

8.2

Boarding

7.9

Reviews

1 / 10

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

7.5
Good
820 reviews
7.7
Good
1,658 reviews

Comfort

7.5

Entertainment

6.9

Overall

7.7

Food

7.0

Crew

8.2

Boarding

7.9

Reviews

1 / 10

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

7.5
Good
1,849 reviews
7.7
Good
1,658 reviews

Comfort

7.5

Entertainment

6.9

Overall

7.7

Food

7.0

Crew

8.2

Boarding

7.9

Reviews

1 / 10

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

7.4
Good
8,965 reviews
7.7
Good
1,658 reviews

Comfort

7.5

Entertainment

6.9

Overall

7.7

Food

7.0

Crew

8.2

Boarding

7.9

Reviews

1 / 10

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How popular is this Mexico City to Santiago flight route?

  • What are the cheapest airlines flying from Mexico City to Santiago round-trip?

    Flying on Copa Airlines is currently your cheapest option to Santiago, with prices starting at C$ 749. Additional round-trip tickets that might be worth considering are offered by Avianca and LATAM Airlines, with the lowest prices starting at C$ 808 and C$ 838, respectively. Users have found that Copa Airlines is 16% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Mexico City to Santiago one-way?

    To fly one-way, consider booking your trip with Copa Airlines, which is currently one of the cheapest options available, starting at C$ 812. Aeromexico flights start at C$ 857 while deals on Qantas Airways start at C$ 3,251 one-way.

  • What are the most reliable airlines from Mexico City to Santiago?

    Consider LATAM Airlines (95%), WestJet (85%) or Aeromexico (76%) when booking your flight. These represent the most reliable airlines when flying from Mexico City to Santiago.

  • Can I find deals for flights from Mexico City to Santiago that include hotel bookings?

    Yes. In addition to deals on Mexico City to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Santiago.

  • Can I find deals for business class flights from Mexico City to Santiago?

    Yes. Cheapflights offers flight deals from Mexico City to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Mexico City to Santiago (average of C$ 628). Flying from Mexico City to Santiago in December is currently the most expensive (average of C$ 907). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Cheapflights does show flights with no change fees to all users. To see these options for flights from Mexico City to Santiago, users can toggle the no change fees filter when performing a flight search.

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Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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