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Cheap flights from Mexico City to Santiago from C$ 567

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 16/4. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — SCL
2 Apr — 9 Apr1
1 adult

Cheap flight deals from Mexico City to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 28 March 2025.

Round-trip from

C$ 689

One-way from

C$ 567

Popular in

December

Cheapest in

August

Average price

C$ 869
Copa Airlines
  • Copa Airlines
  • 10/6-7/8
  • 2 total stops
  • 31h 41m total
  • Mexico City to Santiago
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Copa Airlines
  • Copa Airlines
  • 16/4
  • 1 total stop
  • 15h 44m total
  • Mexico City to Santiago
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Highest demand for flights based on searches. 7% potential increase in price (C$ 101 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease (C$ 19 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Mexico City to Santiago

Cheapest flights from Mexico City to Santiago
Explore the most affordable flight options available from Mexico City to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 March 2025.

Thu 10/44:55 a.m.MEX - SCL
1 stop15h 35mAvianca
Sat 19/46:10 a.m.SCL - MEX
1 stop13h 55mAvianca
Deal found 27/3C$ 1,076
Sun 19/101:40 a.m.MEX - SCL
1 stop19h 00mCopa Airlines
Fri 24/1012:27 p.m.SCL - MEX
1 stop15h 33mCopa Airlines
Deal found 27/3C$ 1,079
Sun 25/55:20 p.m.MEX - SCL
1 stop24h 10mLATAM Airlines
Fri 30/58:10 a.m.SCL - MEX
Nonstop8h 45mLATAM Airlines
Deal found 27/3C$ 1,085
Mon 3/1110:05 a.m.MEX - SCL
Nonstop8h 10mAeromexico
Sun 16/1111:25 p.m.SCL - MEX
Nonstop8h 35mAeromexico
Deal found 27/3C$ 1,105
Fri 24/105:15 p.m.MEX - SCL
2 stops59h 35mUnited Airlines
Sun 2/1110:45 p.m.SCL - MEX
2 stops50h 05mUnited Airlines
Deal found 27/3C$ 2,434
Fri 8/88:40 a.m.MEX - SCL
3 stops34h 35mMultiple Airlines
Fri 22/87:05 a.m.SCL - MEX
2 stops32h 10mMultiple Airlines
Deal found 27/3C$ 3,373
Tue 6/510:00 p.m.MEX - SCL
2 stops34h 30mBritish Airways
Sat 24/55:05 a.m.SCL - MEX
2 stops40h 40mBritish Airways
Deal found 27/3C$ 10,585
Fri 24/101:55 p.m.MEX - SCL
2 stops41h 50mQantas Airways
Wed 29/1012:40 a.m.SCL - MEX
2 stops46h 54mQantas Airways
Deal found 28/3C$ 15,472

Cheapflights Fare Finder

Customize your flight search to find flights from Mexico City to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 28 March 2025.
Use the filters below to find and compare flights from Mexico City to Santiago that are best for you.

Fly from

Mexico City

Fly to

Santiago

Route

Depart

Return

Price

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Sun 25/5

5:20 p.m.-1:30 p.m.

2 stops18h 10m

Santiago Arturo Merino Benitez

Fri 30/5

2:30 p.m.-3:35 p.m.

2 stops27h 05m

C$ 1,131

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Mon 21/4

9:50 a.m.-11:11 p.m.

1 stop11h 21m

Santiago Arturo Merino Benitez

Sun 27/4

12:30 a.m.-2:30 p.m.

1 stop16h 00m

C$ 1,169

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Sat 24/5

12:40 a.m.-4:15 a.m.

1 stop25h 35m

Santiago Arturo Merino Benitez

Fri 30/5

5:55 a.m.-1:55 a.m.

2 stops22h 00m

C$ 1,198

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Fri 8/8

8:40 a.m.-9:15 p.m.

3 stops34h 35m

Santiago Arturo Merino Benitez

Fri 22/8

7:05 a.m.-1:15 p.m.

2 stops32h 10m

C$ 3,373

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Sun 4/5

6:55 p.m.-4:05 p.m.

2 stops43h 10m

Santiago Arturo Merino Benitez

Wed 7/5

9:35 p.m.-10:00 a.m.

2 stops38h 25m

C$ 4,442

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Tue 6/5

10:00 p.m.-10:30 a.m.

2 stops34h 30m

Santiago Arturo Merino Benitez

Sat 24/5

5:05 a.m.-7:45 p.m.

2 stops40h 40m

C$ 10,585

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Wed 16/4

1:40 a.m.-7:24 p.m.

1 stop15h 44m

C$ 567

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Tue 22/4

5:15 p.m.-2:20 p.m.

3 stops43h 05m

C$ 3,239

Flights are sorted by cheapest round-trip flights first.

Deals found on 27/3

Best time to book a flight from Mexico City to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Santiago

How far ahead should I book a flight from Mexico City to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Mexico City to Santiago. Price data was last updated on 21 March 2025.

The price you pay for your flight from Mexico City to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 83 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Mexico City to Santiago?

Currently, April is the cheapest month in which you can book a flight from Mexico City to Santiago (average of C$ 628). Flying from Mexico City to Santiago in December is currently the most expensive (average of C$ 905). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MEX to SCL?

Find hourly flight availability from Mexico City to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 28 March 2025.

When flying from Mexico City to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 70.0 mm per month. June is typically the wettest month, when rainfall can reach 70.0 mm. January is typically the driest time to visit Santiago when rainfall is around 0.0 mm.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 21.0 C. Travellers hoping to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 8.0 C).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated 28 March 2025.
LATAM Airlines
7.5
Good
1,750 reviews
Check prices

Entertainment

7.0

Overall

7.5

Food

6.7

Comfort

7.4

Crew

8.1

Boarding

7.6

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
LATAM Airlines
7.5
Good
1,750 reviews
LATAM Airlines
7.5
Good
1,750 reviews
Check prices

Entertainment

7.0

Overall

7.5

Food

6.7

Comfort

7.4

Crew

8.1

Boarding

7.6

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
Qantas Airways
7.5
Good
811 reviews
LATAM Airlines
7.5
Good
1,750 reviews
Check prices

Entertainment

7.0

Overall

7.5

Food

6.7

Comfort

7.4

Crew

8.1

Boarding

7.6

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
Copa Airlines
7.5
Good
1,395 reviews
LATAM Airlines
7.5
Good
1,750 reviews
Check prices

Entertainment

7.0

Overall

7.5

Food

6.7

Comfort

7.4

Crew

8.1

Boarding

7.6

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
Aeromexico
7.5
Good
1,701 reviews
LATAM Airlines
7.5
Good
1,750 reviews
Check prices

Entertainment

7.0

Overall

7.5

Food

6.7

Comfort

7.4

Crew

8.1

Boarding

7.6

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
Avianca
6.7
Okay
2,300 reviews
LATAM Airlines
7.5
Good
1,750 reviews
Check prices

Entertainment

7.0

Overall

7.5

Food

6.7

Comfort

7.4

Crew

8.1

Boarding

7.6

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Mexico City to Santiago flight route?

    This flight path from Mexico City Benito Juarez to Santiago Arturo Merino Benitez was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Mexico City to Santiago round-trip?

    Flying on Copa Airlines is currently your cheapest option to Santiago, with prices starting at C$ 689. Additional round-trip tickets that might be worth considering are offered by Avianca and LATAM Airlines, with the lowest prices starting at C$ 965 and C$ 1,066, respectively. Users have found that Copa Airlines is 23% cheaper than the other options available to this destination.

  • What are the most reliable airlines from Mexico City to Santiago?

    Consider WestJet (92%), Aeromexico (92%) or LATAM Airlines (90%) when booking your flight. These represent the most reliable airlines when flying from Mexico City to Santiago.

  • Can I find deals for flights from Mexico City to Santiago that include hotel bookings?

    Yes. In addition to deals on Mexico City to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Santiago.

  • Can I find deals for business class flights from Mexico City to Santiago?

    Yes. Cheapflights offers flight deals from Mexico City to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Mexico City to Santiago (average of C$ 628). Flying from Mexico City to Santiago in December is currently the most expensive (average of C$ 905). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Deals for Mexico City to Santiago flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Mexico City to Santiago?

Cheapflights simply makes it quick and affordable to book flights from Mexico City to Santiago by bringing together all flight options from hundreds of airlines and agencies online — and put it in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Mexico City to Santiago with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Mexico City to Santiago, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Mexico City to Santiago become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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