What are the cheapest airlines to fly from Buffalo to South Carolina one-way?

The cheapest airlines for a one-way flight from Buffalo to South Carolina are Frontier (C$ 125), Delta (C$ 179), and Southwest (C$ 197).

What are the most popular routes from Buffalo to South Carolina?

When deciding which route to take from Buffalo to South Carolina consider Buffalo - Charlotte Douglas, Buffalo - Charleston or Buffalo - Myrtle Beach Intl as they are the most popular.

What are the most popular airlines that fly from Buffalo to South Carolina?

The most popular airlines flying from Buffalo to South Carolina are American Airlines, United Airlines and Southwest. Something to consider prior to booking your flight.

How far in advance should I book a flight from Buffalo to South Carolina?

To save on the cost of your flight from Buffalo to South Carolina, book at least 29 days before your planned departure. Booking around this time can save you about 86% on the cost of this flight compared to booking a flight leaving this week. We have found prices from C$ 584 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as C$ 797.

What is the cheapest month to fly from Buffalo to South Carolina?

Flights from Buffalo to South Carolina lean towards being more expensive in April. Prices are generally better when you fly from Buffalo to South Carolina in September, with the cheapest ticket starting at C$ 271.

What airport do you fly from for flights from Buffalo to South Carolina?

For a flight from Buffalo to South Carolina, you will be flying from Buffalo. Buffalo (BUF) is just 13.4 km from the centre of the city.

Can I find deals for flights from Buffalo to South Carolina that include hotel bookings?

Yes. In addition to deals on Buffalo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Buffalo to South Carolina?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to South Carolina.

Can I find deals for business class flights from Buffalo to South Carolina?

Yes. Cheapflights offers flight deals from Buffalo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

C$ 125+ Flights from Buffalo to South Carolina - Compare & Save Big

Cheap flight deals from Buffalo to South Carolina

Round-trip from	C$ 256
One-way from	C$ 125
Popular in	April
Cheapest in	September
Average price	C$ 590

JetBlue
10/6-17/6
2 total stops
13h 14m total
Buffalo to South Carolina

Search Deals

Frontier
17/5
1 total stop
6h 14m total
Buffalo to South Carolina

Search Deals

Highest demand for flights based on searches. 8% potential increase in price (C$ 64 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease (C$ 12 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

Search Deals

Find flight deals from Buffalo to South Carolina

Cheapest flights from Buffalo to South Carolina
Explore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 April 2025.

Tue 10/66:00 a.m.BUF - SAV

1 stop5h 40mJetBlue

Tue 17/611:24 a.m.SAV - BUF

1 stop7h 34mJetBlue

Deal found 29/4C$ 256

Fri 16/57:28 p.m.BUF - CLT

1 stop22h 24mFrontier

Sun 18/510:36 p.m.CLT - BUF

1 stop10h 25mFrontier

Deal found 28/4C$ 264

Fri 4/75:40 a.m.BUF - CHS

1 stop4h 35mJetBlue

Wed 9/76:59 p.m.CHS - BUF

1 stop5h 00mJetBlue

Deal found 29/4C$ 275

Sun 29/67:00 a.m.BUF - SAV

1 stop7h 34mUnited Airlines

Tue 1/77:07 p.m.SAV - BUF

1 stop4h 37mUnited Airlines

Deal found 28/4C$ 296

Fri 30/56:35 p.m.BUF - SAV

1 stop5h 26mDelta

Tue 3/65:30 a.m.SAV - BUF

1 stop5h 30mDelta

Deal found 28/4C$ 309

Thu 10/78:30 p.m.BUF - CHS

1 stop4h 25mSouthwest

Sun 13/77:05 p.m.CHS - BUF

1 stop5h 55mSouthwest

Deal found 29/4C$ 328

Wed 2/71:48 p.m.BUF - CLT

Nonstop1h 52mAmerican Airlines

Tue 8/74:45 p.m.CLT - BUF

Nonstop1h 49mAmerican Airlines

Deal found 29/4C$ 352

Tue 27/55:55 a.m.BUF - MYR

1 stop4h 30mSouthwest

Tue 3/66:05 p.m.MYR - BUF

1 stop4h 30mSouthwest

Deal found 29/4C$ 356

Tue 27/56:00 a.m.BUF - MYR

1 stop6h 23mDelta

Tue 3/66:00 a.m.MYR - BUF

2 stops8h 19mDelta

Deal found 29/4C$ 363

Sun 2/115:45 a.m.BUF - SAV

1 stop4h 35mSouthwest

Sun 9/117:55 a.m.SAV - BUF

1 stop4h 05mSouthwest

Deal found 28/4C$ 365

Wed 2/72:05 p.m.BUF - CLT

1 stop6h 25mSouthwest

Tue 8/76:55 p.m.CLT - BUF

1 stop4h 00mSouthwest

Deal found 29/4C$ 378

Wed 21/52:25 p.m.BUF - MYR

2 stops8h 06mAmerican Airlines

Sat 31/56:35 p.m.MYR - BUF

1 stop5h 39mAmerican Airlines

Deal found 28/4C$ 383

Best flights from Buffalo to South Carolina
Discover carefully curated flight deals from Buffalo to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 30 April 2025.

Tue 10/66:00 a.m.BUF - SAV

1 stop5h 40mJetBlue

Tue 17/611:24 a.m.SAV - BUF

1 stop7h 34mJetBlue

Deal found 28/4C$ 256

Fri 16/57:28 p.m.BUF - CLT

1 stop22h 24mFrontier

Sun 18/510:36 p.m.CLT - BUF

1 stop10h 25mFrontier

Deal found 28/4C$ 264

Sun 29/67:00 a.m.BUF - SAV

1 stop7h 34mUnited Airlines

Tue 1/77:07 p.m.SAV - BUF

1 stop4h 37mUnited Airlines

Deal found 28/4C$ 296

Fri 30/56:35 p.m.BUF - SAV

1 stop5h 26mDelta

Tue 3/65:30 a.m.SAV - BUF

1 stop5h 30mDelta

Deal found 28/4C$ 309

Thu 10/78:30 p.m.BUF - CHS

1 stop4h 25mSouthwest

Sun 13/77:05 p.m.CHS - BUF

1 stop5h 55mSouthwest

Deal found 29/4C$ 328

Wed 2/71:48 p.m.BUF - CLT

Nonstop1h 52mAmerican Airlines

Tue 8/74:45 p.m.CLT - BUF

Nonstop1h 49mAmerican Airlines

Deal found 29/4C$ 352

Fri 4/75:40 a.m.BUF - CHS

1 stop4h 35mJetBlue

Wed 9/76:59 p.m.CHS - BUF

1 stop5h 00mJetBlue

Deal found 29/4C$ 275

Tue 27/55:55 a.m.BUF - MYR

1 stop4h 30mSouthwest

Tue 3/66:05 p.m.MYR - BUF

1 stop4h 30mSouthwest

Deal found 29/4C$ 356

Tue 27/56:00 a.m.BUF - MYR

1 stop6h 23mDelta

Tue 3/66:00 a.m.MYR - BUF

2 stops8h 19mDelta

Deal found 29/4C$ 363

Wed 21/52:25 p.m.BUF - MYR

2 stops8h 06mAmerican Airlines

Sat 31/56:35 p.m.MYR - BUF

1 stop5h 39mAmerican Airlines

Deal found 28/4C$ 383

Wed 4/66:15 a.m.BUF - CLT

2 stops9h 59mUnited Airlines

Sat 7/611:08 a.m.CLT - BUF

1 stop5h 47mUnited Airlines

Deal found 27/4C$ 385

Wed 2/72:05 p.m.BUF - CLT

1 stop6h 25mSouthwest

Tue 8/76:55 p.m.CLT - BUF

1 stop4h 00mSouthwest

Deal found 29/4C$ 378

Last-minute flights from Buffalo to South Carolina
Discover last-minute flight deals from Buffalo to South Carolina. Data last updated 30 April 2025 and is based on user searches.

Mon 5/59:51 a.m.BUF - CLT

1 stop5h 40mFrontier

Thu 8/510:36 p.m.CLT - BUF

1 stop10h 25mFrontier

Deal found 29/4C$ 375

Mon 5/57:11 p.m.BUF - CLT

Nonstop1h 56mAmerican Airlines

Thu 8/59:20 a.m.CLT - BUF

Nonstop1h 56mAmerican Airlines

Deal found 29/4C$ 908

Tue 6/54:15 p.m.BUF - CLT

1 stop4h 05mSouthwest

Wed 7/57:00 a.m.CLT - BUF

1 stop3h 20mSouthwest

Deal found 28/4C$ 407

Tue 6/55:55 a.m.BUF - MYR

1 stop4h 30mSouthwest

Fri 9/512:40 p.m.MYR - BUF

1 stop6h 35mSouthwest

Deal found 28/4C$ 663

Wed 7/56:05 a.m.BUF - MYR

1 stop5h 26mDelta

Tue 13/511:03 a.m.MYR - BUF

2 stops12h 10mDelta

Deal found 28/4C$ 587

Fri 9/55:45 a.m.BUF - CHS

1 stop4h 20mSouthwest

Fri 16/55:00 p.m.CHS - BUF

1 stop5h 40mSouthwest

Deal found 29/4C$ 494

Fri 9/53:35 p.m.BUF - SAV

1 stop5h 55mSouthwest

Sun 11/56:40 p.m.SAV - BUF

1 stop4h 35mSouthwest

Deal found 28/4C$ 646

Fri 9/57:55 p.m.BUF - CHS

1 stop3h 55mUnited Airlines

Mon 12/56:30 a.m.CHS - BUF

2 stops12h 21mUnited Airlines

Deal found 30/4C$ 698

Fri 9/56:00 a.m.BUF - CLT

1 stop3h 45mUnited Airlines

Fri 16/57:31 p.m.CLT - BUF

1 stop4h 26mUnited Airlines

Deal found 28/4C$ 746

Wed 14/56:05 a.m.BUF - CHS

1 stop6h 56mDelta

Sun 18/55:35 a.m.CHS - BUF

1 stop5h 23mDelta

Deal found 29/4C$ 394

Fri 16/57:28 p.m.BUF - CLT

1 stop22h 24mFrontier

Sun 18/510:36 p.m.CLT - BUF

1 stop10h 25mFrontier

Deal found 28/4C$ 264

Wed 21/52:25 p.m.BUF - MYR

2 stops8h 06mAmerican Airlines

Sat 31/56:35 p.m.MYR - BUF

1 stop5h 39mAmerican Airlines

Deal found 28/4C$ 383

One-way flights from Buffalo to South Carolina
Search for one-way flight options from Buffalo to South Carolina. Find affordable one-way fares based on user searches. Data last updated 30 April 2025.

Sat 17/511:38 a.m.BUF - CLT

1 stop6h 14mFrontier

Deal found 29/4C$ 125

Tue 10/66:00 a.m.BUF - MYR

1 stop4h 15mDelta

Deal found 28/4C$ 179

Wed 2/710:38 a.m.BUF - CLT

1 stop5h 29mDelta

Deal found 28/4C$ 190

Tue 20/55:55 a.m.BUF - CLT

1 stop4h 30mSouthwest

Deal found 29/4C$ 197

Thu 15/56:35 p.m.BUF - CHS

1 stop4h 00mDelta

Deal found 29/4C$ 198

Thu 10/73:40 p.m.BUF - CHS

2 stops9h 15mSouthwest

Deal found 29/4C$ 237

Sun 8/67:00 a.m.BUF - MYR

1 stop7h 35mUnited Airlines

Deal found 28/4C$ 248

Sun 25/56:15 a.m.BUF - CLT

2 stops9h 59mUnited Airlines

Deal found 28/4C$ 259

Thu 29/56:10 a.m.BUF - CLT

Nonstop1h 55mAmerican Airlines

Deal found 29/4C$ 262

Thu 24/711:15 a.m.BUF - MYR

2 stops10h 20mSouthwest

Deal found 28/4C$ 275

Fri 16/56:00 a.m.BUF - SAV

1 stop4h 59mUnited Airlines

Deal found 28/4C$ 486

Thu 10/75:54 p.m.BUF - CHS

3 stops20h 31mUnited Airlines

Deal found 29/4C$ 588

Cheapflights Fare Finder

Use the filters below to find and compare flights from Buffalo to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Tue 10/6

6:00 a.m.-11:40 a.m.

1 stop5h 40m

Savannah/Hilton Head

Tue 17/6

11:24 a.m.-6:58 p.m.

1 stop7h 34m

C$ 256

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Fri 16/5

7:28 p.m.-5:52 p.m.

1 stop22h 24m

Charlotte Douglas

Sun 18/5

10:36 p.m.-9:01 a.m.

1 stop10h 25m

C$ 264

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Fri 4/7

5:40 a.m.-10:15 a.m.

1 stop4h 35m

Charleston

Wed 9/7

6:59 p.m.-11:59 p.m.

1 stop5h 00m

C$ 275

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Sun 29/6

7:00 a.m.-2:34 p.m.

1 stop7h 34m

Savannah/Hilton Head

Tue 1/7

7:07 p.m.-11:44 p.m.

1 stop4h 37m

C$ 296

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Fri 30/5

6:35 p.m.-12:01 a.m.

1 stop5h 26m

Savannah/Hilton Head

Tue 3/6

5:30 a.m.-11:00 a.m.

1 stop5h 30m

C$ 309

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Thu 10/7

8:30 p.m.-12:55 a.m.

1 stop4h 25m

Charleston

Sun 13/7

7:05 p.m.-1:00 a.m.

1 stop5h 55m

C$ 328

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Wed 2/7

1:48 p.m.-3:40 p.m.

Nonstop1h 52m

Charlotte Douglas

Tue 8/7

4:45 p.m.-6:34 p.m.

Nonstop1h 49m

C$ 352

BuffaloMyrtle Beach

BUF - MYR

BUFMYR

Buffalo

Tue 27/5

5:55 a.m.-10:25 a.m.

1 stop4h 30m

Myrtle Beach Intl

Tue 3/6

6:05 p.m.-10:35 p.m.

1 stop4h 30m

C$ 356

BuffaloMyrtle Beach

BUF - MYR

BUFMYR

Buffalo

Tue 27/5

6:00 a.m.-12:23 p.m.

1 stop6h 23m

Myrtle Beach Intl

Tue 3/6

6:00 a.m.-2:19 p.m.

2 stops8h 19m

C$ 363

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Wed 2/7

2:05 p.m.-8:30 p.m.

1 stop6h 25m

Charlotte Douglas

Tue 8/7

6:55 p.m.-10:55 p.m.

1 stop4h 00m

C$ 378

Flights are sorted by cheapest round-trip flights first.

Deals found on 29/4

Showing 1-10 of 29 results

Best time to book a flight from Buffalo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Buffalo with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to South Carolina

What is the cheapest month to book a flight from Buffalo to South Carolina?

Currently, September is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of C$ 407). Flying from Buffalo to South Carolina in May is currently the most expensive (average of C$ 542). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to SC?

When flying from Buffalo to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

In terms of precipitation, rainfall in South Carolina ranges from 76.0 - 165.0 mm per month. July is typically the wettest month, when rainfall can reach 165.0 mm. November is typically the driest time to visit South Carolina when rainfall is around 76.0 mm.

Temperature in South Carolina by month

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 26.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 7.0 C).

Reviews of airlines servicing South Carolina

Peruse reviews from past customers who have flown with Southwest, Delta and United Airlines from Buffalo to South Carolina to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,295 reviews

Check prices

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Southwest

8.0

Very good

4,295 reviews

Southwest

8.0

Very good

4,295 reviews

Check prices

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Delta

8.0

Very good

7,929 reviews

Southwest

8.0

Very good

4,295 reviews

Check prices

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

United Airlines

7.4

Good

8,696 reviews

Southwest

8.0

Very good

4,295 reviews

Check prices

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

JetBlue

7.3

Good

2,922 reviews

Southwest

8.0

Very good

4,295 reviews

Check prices

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,295 reviews

Check prices

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

What airport do you fly from for flights from Buffalo to South Carolina?
For a flight from Buffalo to South Carolina, you will be flying from Buffalo. Buffalo (BUF) is just 13.4 km from the centre of the city.
What are the cheapest airlines to fly from Buffalo to South Carolina one-way?
The cheapest airlines for a one-way flight from Buffalo to South Carolina are Frontier (C$ 125), Delta (C$ 179), and Southwest (C$ 197).
What are the most popular routes from Buffalo to South Carolina?
When deciding which route to take from Buffalo to South Carolina consider Buffalo - Charlotte Douglas, Buffalo - Charleston or Buffalo - Myrtle Beach Intl as they are the most popular.
Can I find deals for flights from Buffalo to South Carolina that include hotel bookings?
Yes. In addition to deals on Buffalo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Buffalo to South Carolina?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to South Carolina.
Can I find deals for business class flights from Buffalo to South Carolina?
Yes. Cheapflights offers flight deals from Buffalo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Buffalo to South Carolina?
Currently, September is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of C$ 407). Flying from Buffalo to South Carolina in May is currently the most expensive (average of C$ 542). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

South Carolina car rentals

Charleston Airport car rentals

Myrtle Beach Intl Airport car rentals

Greenville Airport car rentals

Columbia Metropolitan Airport car rentals

Hilton Head Island Airport car rentals

Florence Airport car rentals

Myrtle Beach car rentals

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Columbia car rentals

Direct flights to United States

Top 4 airlines flying from Buffalo to South Carolina

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	CheapestC$ 244	AverageC$ 416	FlexibilityNo cancel fee	On-time71%	Search American Airlines flights
Delta	CheapestC$ 255	AverageC$ 437	FlexibilityNo cancel fee	On-timeN/A	Search Delta flights
Southwest	CheapestC$ 348	AverageC$ 539	FlexibilityNo cancel fee	On-time63%	Search Southwest flights
United Airlines	CheapestC$ 356	AverageC$ 678	FlexibilityNo cancel fee	On-time69%	Search United Airlines flights

Fly with Cheapflights

How does Cheapflights help users find flights from Buffalo to South Carolina?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Buffalo to South Carolina. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Buffalo to South Carolina?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Buffalo to South Carolina for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Buffalo to South Carolina with no change fees?

Certainly. Search results for flights to South Carolina from Buffalo shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Buffalo to South Carolina become cheaper?

Yes, Cheapflights offers price alerts on Buffalo to South Carolina flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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Cheap flights from Buffalo to South Carolina from C$ 125

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 17/5. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Buffalo to South Carolina

Keep the following information in mind while searching for Buffalo to South Carolina flight deals. Data was last updated 30 April 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Buffalo to South Carolina

Cheapest flights from Buffalo to South CarolinaExplore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 April 2025.

Explore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 April 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Buffalo to South Carolina that are best for you.

Best time to book a flight from Buffalo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Buffalo with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to South Carolina

What is the cheapest month to book a flight from Buffalo to South Carolina?

What is the cheapest time of day to fly from BUF to SC?

Find hourly flight availability from Buffalo to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 30 April 2025.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

Reviews of airlines servicing South Carolina

Peruse reviews from past customers who have flown with Southwest, Delta and United Airlines from Buffalo to South Carolina to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Buffalo to South Carolina?

What are the cheapest airlines to fly from Buffalo to South Carolina one-way?

What are the most popular routes from Buffalo to South Carolina?

Can I find deals for flights from Buffalo to South Carolina that include hotel bookings?

How can I find direct flights from Buffalo to South Carolina?

Can I find deals for business class flights from Buffalo to South Carolina?

What is the cheapest month to book a flight from Buffalo to South Carolina?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Buffalo to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Buffalo to South Carolina

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How does Cheapflights help users find flights from Buffalo to South Carolina?

Why should you use Cheapflights to find cheap flight tickets from Buffalo to South Carolina?

Can Cheapflights find flights from Buffalo to South Carolina with no change fees?

Can Cheapflights notify me if prices for flights from Buffalo to South Carolina become cheaper?

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Cheapest flights from Buffalo to South Carolina
Explore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 April 2025.