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Cheap flights from Buffalo to South Carolina from C$ 142

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — CHS
25 Feb — 4 Mar1
1 adult

Cheap flight deals from Buffalo to South Carolina

Keep the following information in mind while searching for Buffalo to South Carolina flight deals. Data was last updated 20 February 2025.

Round-trip from

C$ 260

One-way from

C$ 142

Popular in

April

Cheapest in

September

Average price

C$ 536
Delta
  • Delta
  • 10/3-19/3
  • 2 total stops
  • 22h 53m total
  • Buffalo to South Carolina
Search Deals
American Airlines
  • American Airlines
  • 6/3
  • 1 total stop
  • 5h 07m total
  • Buffalo to South Carolina
Search Deals
Highest demand for flights based on searches. 7% potential increase in price (C$ 56 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (C$ 9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2025
Search Deals

Find flight deals from Buffalo to South Carolina

Cheapest flights from Buffalo to South Carolina
Explore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 20 February 2025.

Mon 10/37:00 a.m.BUF - CHS
1 stop14h 52mDelta
Wed 19/310:00 a.m.CHS - BUF
1 stop8h 01mDelta
Deal found 20/2C$ 260
Mon 17/37:00 a.m.BUF - SAV
1 stop14h 16mDelta
Wed 19/36:00 a.m.SAV - BUF
1 stop12h 01mDelta
Deal found 20/2C$ 288
Sun 16/312:15 p.m.BUF - CHS
1 stop6h 49mJetBlue
Thu 20/36:00 a.m.CHS - BUF
1 stop5h 30mJetBlue
Deal found 20/2C$ 328
Mon 7/46:10 a.m.BUF - CLT
Nonstop1h 57mAmerican Airlines
Wed 9/47:26 a.m.CLT - BUF
Nonstop1h 38mAmerican Airlines
Deal found 19/2C$ 351
Tue 8/41:50 p.m.BUF - CLT
1 stop5h 30mSouthwest
Wed 9/47:00 a.m.CLT - BUF
1 stop3h 20mSouthwest
Deal found 19/2C$ 372
Thu 6/36:22 a.m.BUF - CLT
1 stop5h 42mDelta
Sun 9/311:14 a.m.CLT - BUF
1 stop6h 47mDelta
Deal found 20/2C$ 374
Thu 15/57:21 p.m.BUF - CHS
1 stop4h 54mAmerican Airlines
Mon 19/56:09 p.m.CHS - BUF
1 stop6h 06mAmerican Airlines
Deal found 20/2C$ 385
Thu 6/31:10 p.m.BUF - CLT
2 stops10h 49mUnited Airlines
Sun 9/36:00 a.m.CLT - BUF
1 stop3h 52mUnited Airlines
Deal found 20/2C$ 396
Thu 8/511:20 a.m.BUF - SAV
1 stop6h 50mSouthwest
Sun 11/56:30 a.m.SAV - BUF
1 stop4h 20mSouthwest
Deal found 20/2C$ 403
Wed 5/36:00 a.m.BUF - SAV
1 stop4h 43mUnited Airlines
Thu 13/35:40 a.m.SAV - BUF
2 stops6h 37mUnited Airlines
Deal found 19/2C$ 435
Sun 13/47:19 p.m.BUF - SAV
1 stop4h 30mAmerican Airlines
Tue 22/48:33 p.m.SAV - BUF
1 stop3h 58mAmerican Airlines
Deal found 20/2C$ 439
Sun 11/56:00 a.m.BUF - MYR
1 stop4h 12mAmerican Airlines
Sat 17/57:54 p.m.MYR - BUF
1 stop4h 21mAmerican Airlines
Deal found 19/2C$ 449

Find flights from Buffalo to South Carolina within your budget

Customize your flight search to find flights from Buffalo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 20 February 2025.

Fly from

Buffalo

Fly to

South Carolina

Route

Depart

Return

Price

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Mon 10/3

7:00 a.m.-9:52 p.m.

1 stop14h 52m

Charleston

Wed 19/3

10:00 a.m.-6:01 p.m.

1 stop8h 01m

C$ 260

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Mon 17/3

7:00 a.m.-9:16 p.m.

1 stop14h 16m

Savannah/Hilton Head

Wed 19/3

6:00 a.m.-6:01 p.m.

1 stop12h 01m

C$ 288

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Sun 16/3

12:15 p.m.-7:04 p.m.

1 stop6h 49m

Charleston

Thu 20/3

6:00 a.m.-11:30 a.m.

1 stop5h 30m

C$ 328

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Mon 7/4

6:10 a.m.-8:07 a.m.

Nonstop1h 57m

Charlotte Douglas

Wed 9/4

7:26 a.m.-9:04 a.m.

Nonstop1h 38m

C$ 351

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Tue 8/4

1:50 p.m.-7:20 p.m.

1 stop5h 30m

Charlotte Douglas

Wed 9/4

7:00 a.m.-10:20 a.m.

1 stop3h 20m

C$ 372

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Thu 6/3

6:22 a.m.-12:04 p.m.

1 stop5h 42m

Charlotte Douglas

Sun 9/3

11:14 a.m.-6:01 p.m.

1 stop6h 47m

C$ 374

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Thu 15/5

7:21 p.m.-12:15 a.m.

1 stop4h 54m

Charleston

Mon 19/5

6:09 p.m.-12:15 a.m.

1 stop6h 06m

C$ 385

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Thu 6/3

1:10 p.m.-11:59 p.m.

2 stops10h 49m

Charlotte Douglas

Sun 9/3

6:00 a.m.-9:52 a.m.

1 stop3h 52m

C$ 396

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Thu 8/5

11:20 a.m.-6:10 p.m.

1 stop6h 50m

Savannah/Hilton Head

Sun 11/5

6:30 a.m.-10:50 a.m.

1 stop4h 20m

C$ 403

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Wed 5/3

6:00 a.m.-10:43 a.m.

1 stop4h 43m

Savannah/Hilton Head

Thu 13/3

5:40 a.m.-12:17 p.m.

2 stops6h 37m

C$ 435

Flights are sorted by cheapest round-trip flights first.

Deals found on 20/2

Showing 1-10 of 30 results
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Best time to book a flight from Buffalo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Buffalo to South Carolina

Get recent, data-driven insights about flights from Buffalo to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Buffalo to South Carolina?

Currently, September is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of C$ 407). Flying from Buffalo to South Carolina in March is currently the most expensive (average of C$ 560). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to SC?

Find hourly flight availability from Buffalo to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 20 February 2025.

When flying from Buffalo to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 76.0 - 165.0 mm per month. July is typically the wettest month, when rainfall can reach 165.0 mm. November is typically the driest time to visit South Carolina when rainfall is around 76.0 mm.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 26.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 7.0 C).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated 20 February 2025.
Peruse reviews from past customers who have flown with Southwest, Delta and JetBlue from Buffalo to South Carolina to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews
Check prices

Comfort

8.1

Food

7.1

Entertainment

7.6

Overall

8.1

Crew

8.7

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews
Check prices

Comfort

8.1

Food

7.1

Entertainment

7.6

Overall

8.1

Crew

8.7

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,220 reviews
Southwest
8.1
Very good
4,411 reviews
Check prices

Comfort

8.1

Food

7.1

Entertainment

7.6

Overall

8.1

Crew

8.7

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

JetBlue
7.4
Good
3,070 reviews
Southwest
8.1
Very good
4,411 reviews
Check prices

Comfort

8.1

Food

7.1

Entertainment

7.6

Overall

8.1

Crew

8.7

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,766 reviews
Southwest
8.1
Very good
4,411 reviews
Check prices

Comfort

8.1

Food

7.1

Entertainment

7.6

Overall

8.1

Crew

8.7

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,411 reviews
Check prices

Comfort

8.1

Food

7.1

Entertainment

7.6

Overall

8.1

Crew

8.7

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to South Carolina?

    For a flight from Buffalo to South Carolina, you will be flying from Buffalo. Buffalo (BUF) is just 13.4 km from the centre of the city.

  • What are the cheapest airlines to fly from Buffalo to South Carolina one-way?

    The cheapest airlines for a one-way flight from Buffalo to South Carolina are American Airlines (C$ 142), JetBlue (C$ 145), and Delta (C$ 155).

  • What are the most popular routes from Buffalo to South Carolina?

    When deciding which route to take from Buffalo to South Carolina consider Buffalo - Charlotte Douglas, Buffalo - Myrtle Beach Intl or Buffalo - Savannah/Hilton Head as they are the most popular.

  • Can I find deals for flights from Buffalo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Buffalo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to South Carolina.

  • Can I find deals for business class flights from Buffalo to South Carolina?

    Yes. Cheapflights offers flight deals from Buffalo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of C$ 407). Flying from Buffalo to South Carolina in March is currently the most expensive (average of C$ 560). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Buffalo to South Carolina

Discover the top 4 airlines that operate flights from Buffalo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 20 February 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapestC$ 251AverageC$ 448FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
DeltaCheapestC$ 262AverageC$ 417FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
SouthwestCheapestC$ 357AverageC$ 555FlexibilityNo cancel feeOn-time63%
Search Southwest flights
United AirlinesCheapestC$ 365AverageC$ 754FlexibilityNo cancel feeOn-time69%
Search United Airlines flights

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How does Cheapflights help users find flights from Buffalo to South Carolina?

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Why should you use Cheapflights to find cheap flight tickets from Buffalo to South Carolina?

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Can Cheapflights find flights from Buffalo to South Carolina with no change fees?

Certainly. Search results for flights to South Carolina from Buffalo shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Buffalo to South Carolina become cheaper?

Yes, Cheapflights offers price alerts on Buffalo to South Carolina flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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